Fluorescence in situ Hybridization

The fluorescence in situ hybridization (FISH) laboratory at MPLN is led by Dr. Katy Phelan. FISH is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes and has a turnaround time of one to two days.

This branch of cytogenetic analysis is more specific than standard karyotype analysis, enabling analysis of disease-specific abnormalities. Using results from previous testing, specific gene locations can be selected for investigation. FISH is offered for the detection of translocations, microdeletion syndromes, aneuploidy and marker chromosome identification.