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JAK2 and Chronic Myeloproliferative Disorder |
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MPLN offers a PCR-based JAK2 analysis to detect the V617F mutation in the JAK2 gene, which is found in a high percentage of patients with chronic myeloproliferative disorders (CMPDs).
In a large percentage of patients with polycythemia vera (PV), essential thrombocythemia (ET) and chronic idiopathic myelofibrosis (CIMF), classification and diagnosis of CMPDs have become much more specific with the identification and association of a single acquired mutation (V617F) in the JAK2 gene.
 JAK2 test information and specimen requirements »
For more information about the JAK2 test, contact one of our service specialists at 800-932-2943.
Our Testing Resources
 JAK2 mutation information
JAK2 Journal Articles
Frantz C, Sekora DM, Henley DC, Huang CK, Pan Q, Quigley NB, Gorman E, Hubbard RA, Mirza I.2007. Comparative evaluation of three JAK2V617F mutation detection methods. Am J Clin Pathol.128(5):865-74
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