CLINICAL HISTORY:
58-year-old female with thrombocytosis.…
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h/o lung CA s/p taxotere/carboplatin in 2012-13
WBC 2900, HGB 10.1 g/dL, hct 30.6 %, MCV 97.0 fL; plt 56 k; absolute neutrophils 1340, absolute lymphocytes 1200, absolute monocytes 300
Bone marrow submitted
Atypical Megakaryocyte - small and hypolobated
…Implant-associated anaplastic large cell lymphomas represent an extremely rare but well-documented complication of prosthetic breast implants. When presenting as an isolated fluid effusion in the absence of extracapsular tissue invasion or mass lesions, these neoplasms have been associated with a uniquely favorable clinical course.
Clinical History:
… Hemophagocytic Lymphohistiocytosis (HLH) is a potentially fatal hyperinflammatory disease caused by a hyperactive and dysregulated immune response. This persistent elevation of proinflammatory cytokines ultimately results in end organ dysfunction. Although multiple types of HLH have been described, HLH can be broadly classified into primary and secondary forms. Primary forms of HLH are uncommon, typically occur in children, and are associated with genetic abnormalities.…
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Accurate recognition of anal basaloid squamous cell carcinomas (problematically called cloacogentic or transitional in the past), especially their distinction from poorly differentiated adenocarcinoma, urothelial carcinoma and neuroendocrine (oat cell) carcinoma can be difficult. Tumors with this histology can arise in the high anal transition zone (ATZ), which can be difficult to anatomically distinguish from the low-rectum. Therefore, confirmation of this diagnosis requires…
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