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  • Leukemia-Associated Genetic Changes Found in Normal Blood

    Posted on November 16 2011

    Pathology Top Pick

    Recurrent genetic abnormalities including BCR-ABL, PML-RARA, AML1-ETO translocations and MLL and CBFB changes are critical to diagnosis, risk stratifications, therapy and disease monitoring of hematologic malignancies. However, low levels of many leukemia-associated genetic changes are incidentally found in normal, healthy individuals. What is the prevalence of such changes in normal individuals?

    Reporting in the Journal of Molecular Diagnostics, senior…

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