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Dr. Nicholas Potter, MPLN's chief scientific officer and molecular diagnostic director, in conjunction with Qiagen, Inc. and Shiel Medical Laboratory, presented a Poster at the 2009 Association for Molecular Pathology (AMP) meeting.
The poster, co-authored by Potter, three medical technologists at MPLN, and several scientists with Qiagen and Shiel Medical Laboratory, evaluated the feasibility of using the automated QIAsymphony® AXpH sample preparation protocol as an alternative to manual conversion of Preservcyt® specimens for testing with the Hybrid Capture® 2 Assay.
The QIAsymphony applications presented at AMP were for research use only, and not for use in diagnostic procedures.
During the 2009 study, which took place from February to June, 2,104 cervical specimens were collected in PreservCyt. Of those samples, 1,056 were tested at MPLN, 528 specimens at Shiel and 520 specimens were tested at Qiagen. Two population types were tested - ASCUS positive reflex testing and adjunctive screening.
The study concluded that the QI Asymphony AXpH DNA protocol provides a fully automated sample preparation method for cervical PreservCyt samples. It also showed that a complete set of 96 samples can be processed in less than 4.5 hours. |