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MPLN attending AMP 2016 showcasing IgVH SHM by NGS


Posted on November 10, 2016 by J Seabrook

Meet MPLN's Dr. Bevan Tandon at Poster H50 for discussions on IgVH Somatic Hypermutation (SHM) by NGS.

Using a next generation sequencing-based approach to IgVH SHM detection, the MPLN methodology utilizes patient DNA as a sample starting material, eliminating many of the challenges related to RNA-based testing.  Laboratory workflow is streamlined and automated to result in non-subjective data output that includes percentage homology of clonal reads to germline IGH reference sequence, VDJ gene utilization, and frequencies of IGH gene sequences.

Read more about IgVH Somatic Hypermutation testing

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