Molecular Pathology Laboratory Network

Bone Marrow Pathology Consultation

Test Code
BMP P
Associations
Hematologic Malignancies
Methodology
Microscopic evaluation of bone marrow biopsy/clot prep (H&E) and peripheral / aspirate smears; additional stains as required (iron, immunohistochemistry)
CPT Codes
Depending on the services rendered:
88321 – Surgical pathology consultation on previously prepared slides
88323 – Surgical pathology consultation on tissue blocks or unstained slides
88325 – Surgical pathology consultation – Comprehensive with review of records and specimens
88313 xn – Special stain
88342 xn – Immunohistochemistry
Turnaround Time
2-4 days
Specimen Requirements
  • Prepared H&E slides or smears
  • Prepared paraffin block(s)
  • Accompanying history and other medical records
Specimen Stability
Slides or tissue blocks, stable indefinitely at 18-25°C
Storage & Handling
  • Ship samples at ambient temperature.
  • In warm summer months, include a cool pack.
  • Causes for Rejection
    Improper specimen labeling; Inadequate marrow for evaluation; Improper sample submission
    Reference Range
    Active cellular marrow; No cells diagnostic of malignancy
    Related Content
    Cytogenetics; FISH; Flow Cytometry; Immunohistochemistry; Gene rearrangements; Quantitative PCR; Special Stains
    Description
    A board-certified hematopathologist / pathologist evaluates bone marrow morphology for malignancy, dysplasia and non-neoplastic disease.

    Submission of peripheral smears and CBC data are required for optimal interpretations. Results of flow cytometric, immunohistochemical, cytogenetic or molecular analyses, when performed, are integrated in the final report.
    References
    Foucar. (2001). Bone Marrow Pathology 2nd Edition. ASCP Press.

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