Molecular Pathology Laboratory Network

Hematopoetic Markers

I CD10: Common ALL antigen
I CD68: CD68 macrophages
I CD34: CD34 endothelial, stem cells, stromal cells
I CD99: Ewings sarcoma, PNET, ALL
I CD117: CD117 C-kit, (ckit) myeloid and mast cell
I GLYCP: A Glycophorin-A
I MPO: Myeloperoxidase
I TDT: Terminal deoxynucleotidyl transferase
I VWF: Von Willebrand factor VIII

Immunohistochemistry

88342 each marker

Less than 2 days

Indefinitely at room temperature

Inadequate fixation; Improper labeling

Marker and tissue specific

Results are reviewed by a board-certified pathologist to determine if tissues are positive or negative for the marker. These results may be used to assist in determining appropriate patient therapy or treatment. Immunohistochemistry combines the principles of histochemistry with the high degree of molecular specificity of the antibody-antigen reaction. The use of an enhanced-polymer detection system provides many benefits including increased sensitivity, fewer procedural steps as compared to conventional techniques, and a reduction in non-specific background staining.

MPLN offers a range of markers by Immunohistochemistry including hematologic, tissue specific, infectious agents and proliferation antigens.