Apoptosis / Cell Cycle Progression by ImmunohistochemistryAssociations I P21WAF: p21 waf, WAF1, inhibitory gene I P27KIP: p27Kip, kinase inhibitory protein 1 P PERK1/2: pERK1/2, extracellular signal related kinase I PRB: pRb, phosphorylated retiniblastoma suppressor protein Methodology Immunohistochemistry CPT Codes 88342 each marker Turnaround Time 3 days Specimen Requirements
Specimen Stability Indefinitely at room temperature Storage & Handling Ship ambient.In extreme hot weather, ship with a cool pack. Causes for Rejection Inadequate fixation; Improper labeling Description Results are reviewed by a board-certified pathologist to determine if tissues are positive or negative for the marker. These results may be used to assist in determining appropriate patient therapy or treatment.
Immunohistochemistry (IHC) combines the principles of histochemistry with the high degree of molecular specificity of the antibody-antigen reaction. The use of an enhanced-polymer detection system provides many benefits including increased sensitivity, fewer procedural steps as compared to conventional techniques, and a reduction in non-specific background staining. MPLN offers a range of markers by IHC including hematologic, tissue specific, infectious agents and proliferation antigens. References
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