Steroid Sulfatase Deficiency
Test Code
F STS
Test Synonyms
del(X)(p22.32), X-linked ichthyosis
Associations
STS/CEP X
Methodology
Fluorescence in situ Hybridization (FISH)
CPT Codes
88368 x2
Turnaround Time
7-10 days
Specimen Requirements
- 5.0 mL whole blood, sodium heparin
- 20-30 mL amniotic fluid, 2 to 3 sterile tubes
Specimen volume includes chromosome analysis.
Specimen Stability
Stable 18-25°C for 72 hours
Storage & Handling
Ship at ambient. Protect from extreme temperature.
Ship on Saturday for Monday delivery only if sample is protected from extreme temperature.
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Reference Range
See report
Description
X-linked recessive ichthyosis is caused by a deletion of the steroid sulfatase gene located on the X chromosome at the p22.3 location. The abnormality is seen more in males and affects approximately 1 in 6,000.
