Molecular Pathology Laboratory Network

Test Directory

Tests

p21 WAF1, Inhibitory Gene

Test CodeI p21WAF
MethodologyImmunohistochemistry Clone 4D10

p27Kip, Kinase Inhibitory Protein 1 by IHC

Test CodeI p27KIP
Associationskinase inhibitory protein 1
MethodologyImmunohistochemsitry; clone 1B4

p53 deletion 17p13

Category:Oncology
Test CodeF P53
AssociationsChronic lymphocytic leukemia (CLL), B-cell prolymphocytic leukemia (PLL), B-cell lymphoproliferative disorder (LPD), Myeloma
MethodologyFluorescence in situ Hybridization (FISH)

Panhematopoetic Markers by Immunohistochemistry

AssociationsI CD45: CD45 leukocyte common antigen
MethodologyImmunohistochemistry

Paroxysmal Nocturnal Hemoglobinuria (CD55, CD59, FLAER)

Category:Flow Cytometry
Test CodeFLOW PNH
MethodologyFlow cytometry, multiparameter analysis

pERK 1/2, Extracellular Signal Related Kinase

Test CodeI PERK1/2
MethodologyImmunohistochemistry Clone: MAPK-YT

Phelan-McDermid Syndrome, deletion 22q13

Category:Constitutional
Test CodeF PMS
MethodologyFluorescence in situ Hybridization (FISH)

Plasma Cell Markers by Immunohistochemistry

AssociationsI P63PC: Plasma cell p63 I CD138: CD138 plasma cells, subset epithelial cells I KAPLAM: Kappa, Lambda Ig light chains double stain I KAPPA: Kappa immunoglobulin light chains I LAMBDA: Lambda immunoglobulin light chains
MethodologyImmunohistochemistry

PML/RARA Quantitative PCR Disease Monitoring

Test CodeP PMLRARAm
AssociationsAcute promyelocytic leukemia (APL), FAB M3
MethodologyQuantitative reverse transcriptase polymerase chain reaction (qRT-PCR) for PML/RARA t(15;17) long form OR PML/RARA t(15;17) short form

PML/RARA Quantitative PCR Initial Diagnostic Workup

Test CodeP PML RARA
AssociationsAcute promyelocytic leukemia (APL), FAB M3
MethodologyQuantitative reverse transcriptase polymerase chain reaction (qRT-PCR) for PML/RARA t(15;17) long form and PML/RARA t(15;17) short form

PML/RARA t(15,17)

Test CodeF PML/RARA
AssociationsAcute promyelocytic leukemia (APL)
MethodologyFluorescence in situ Hybridization (FISH)

Prader-Willi Syndrome

Category:Constitutional
Test CodeF PWS
Associationsdeletion 15q11
MethodologyFluorescence in situ Hybridization (FISH)

pRb, Phosphorylated Retinoblastoma Suppressor Protein

Test CodeI PRB
MethodologyImmunohistochemistry Clone: EP821Y

ProEx™ C Biomarker by Immunohistochemistry

Test CodeI PROEXC or I PROEXC TC
AssociationsAberrant S phase
MethodologyImmunohistochemistry

Prognostic Markers by Immunohistochemistry

AssociationsI CATH D: Cathepsin D, breast carcinoma I EGFR1: Epidemal growth factor receptor (HER1) I ERCC1:Excision repair cross complementing polypeptide I HER2: HER2/neu (IVD) I MSI: Microsatellite instability - MLH1, MSH2, MSH6 I P53: p53 tumor suppressor g ...
MethodologyImmunohistochemistry

Proliferation Markers by Immunohistochemistry

AssociationsI AKT----Akt, protein kinase B I KI67--- Ki67 (MIB-1) cell proliferation marker I WT1: Wilms tumor
MethodologyImmunohistochemistry

Prostate Markers by Immunohistochemistry

AssociationsI PIN2: PIN-2 cocktail (P504S, CK HMW) I PIN4: PIN-4 cocktail (P504S, CK HMW, P63) I PSA: Prostate specific antigen (PSA) I PSAP: Prostatic acid phosphorase I P504S: P504S gene product (AMACR)
MethodologyImmunohistochemistry

Prostate Specific Antigen, Total

Category:Tumor Markers
Test CodePSA
MethodologyChemiluminescent Immunoassay

PTEN/CEP10 deletion 10q23.3

Category:Breast Cancer
Test CodeF PTEN
AssociationsBreast cancer, endometrial carcimomas, glioblastoma
MethodologyFluorescence in situ Hybridization (FISH)

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