Molecular Pathology Laboratory Network

Breast Cancer

Tests
There are 13 Tests in this Category.

Breast Markers by Immunohistochemistry

AssociationsI AKT: Akt, protein kinase I BRST 2: Cytokeratin 5, p63, CK8/18 breast cocktail I BCL2: BCL2 follicular lymphoma, apoptosis inhibiting protein I BER EP: Epithelial antigen (BER-EP4) I CATHD: Cathepsin D I CD117: c-kit, myeloid and mast cell (CD11 ...
MethodologyImmunohistochemistry

Cancer Antigen 15-3

Test CodeCA153
AssociationsBreast cancer
MethodologyChemiluminescent Immunoassay CA 15-3 is performed by Ascendant Medical Laboratory

Cancer Antigen 27-29

Test CodeC2729
AssociationsBreast cancer
MethodologyChemiluminescent Immunoassay CA 27-29 is performed by Ascendant Medical Laboratory

Carcinoembryonic Antigen

Test CodeCEA
AssociationsColorectal, lung, breast, ovary, uterus
MethodologyChemiluminescent Immunoassay CEA is performed by Ascendant Medical Laboratory

Cell Cycle Analysis; DNA Ploidy and S Phase

Test CodePLOIDY
AssociationsBreast cancer, Non-small cell lung carcinoma, Bladder cancer
MethodologyFlow cytometry analysis

EGFR 7p12 Amplification

Test CodeF EGFR
AssociationsBreast, lung and colon cancer
MethodologyFluorescence in situ Hybridization (FISH)

EGFR Mutation Comprehensive Analysis Exon 18-21

Test CodeP EGFR
AssociationsNSCLC,Non Small-cell Lung Cancer,Response to EGFR tyrosine kinase inhibitors; Gefitinib Erlotinib, IRESSA, Tarceva Responsiveness in NSCLC
MethodologyReal-time Polymerase chain reaction for exon 18-21. EGFR mutation is a referred test.

Epidermal Growth Factor Receptors (HER1) by IHC

Test CodeI HER1
AssociationsPrognostic marker Overexpressed in breast cancer, lung, brain, bladder, gastric, esophagus, cervix, ovary and endometrium.
MethodologyImmunohistochemistry CONFIRM™ anti-Epidermal Growth Factor Receptor (3C6) Primary Antibody.

Estrogen Progesterone Receptors by IHC

Test CodeI ERPR
AssociationsBreast cancer
MethodologyImmunohistochemistry CONFIRM™ anti-Estrogen Receptor (clone SP1)Primary Antibody CONFIRM anti-Progesterone Receptor (clone 1E2) Primary Antibody

HER2 by Immunohistochemistry

Test CodeI HER2 or I HER2 TC
AssociationsBreast cancer, Herceptin
MethodologyImmunohistochemistry

HER2/neu PathVysion®

Test CodeF HER2
AssociationsBreast cancer
MethodologyFluorescence in situ Hybridization (FISH)

PTEN/CEP10 deletion 10q23.3

Test CodeF PTEN
AssociationsBreast cancer, endometrial carcimomas, glioblastoma
MethodologyFluorescence in situ Hybridization (FISH)

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