Cancer Antigen 15-3

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Tumor Markers

Cancer Antigen 15-3

Test Code

CA153

Associations

Breast cancer

Methodology

Chemiluminescent Immunoassay
CA 15-3 is performed by Ascendant Medical Laboratory

CPT Codes

86300 - Immunoassay for tumor antigen, quantitative, CA 15-3

Turnaround Time

Less than 24 hours

Specimen Requirements

7.0 mL serum, gold or red serum separator tube

Specimen Stability

Stable at 4°C for 48 hours

Stable at -20°C for 1 week

Storage & Handling

Centrifuge and refrigerate

Ship on dry ice if frozen or with ice pack at refrigerated temperature

Causes for Rejection

Specimen age or temperature exceeded

Reference Range

See report

Description

Typically, CA 15-3 is used for monitoring advanced stage breast cancer as well as treatment response. The monitoring of this protein level can aid in the management of patient treatment.

References

Park, B et al. (2008). Preoperative CA 15-3 and CEA serum levels as predictor for breast cancer outcomes. Annals of Oncology. 19(4):675-681.
Duffy M.J. (2006). Serum tumor markers in breast cancer: are they of clinical value? Clinical Chemistry. 52:345-351.
Ebeling, FG et al. (2002). Serum CEA and CA 15-3 as prognostic factors in primary breast cancer. British Journal of Cancer. 86:1217–1222.