Breast Cancer

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Breast Markers by Immunohistochemistry

AssociationsI AKT: Akt, protein kinase I BRST 2: Cytokeratin 5, p63, CK8/18 breast cocktail I BCL2: BCL2 follicular lymphoma, apoptosis inhibiting protein I BER EP: Epithelial antigen (BER-EP4) I CATHD: Cathepsin D I CD117: c-kit, myeloid and mast cell (CD11 ...

MethodologyImmunohistochemistry

Cell Cycle Analysis; DNA Ploidy and S Phase

Test CodePLOIDY

AssociationsBreast cancer, Non-small cell lung carcinoma, Bladder cancer

MethodologyFlow cytometry analysis

CellSearch™ - Circulating Tumor Cell Test

Test CodeCELLSEARCH

AssociationsMetastatic breast, colorectal and prostate cancer

MethodologyImmunomagnetic selection and immunofluorescence

EGFR 7p12 Amplification

Test CodeF EGFR

AssociationsBreast, lung and colon cancer

MethodologyFluorescence in situ Hybridization (FISH)

EGFR Mutation Comprehensive Analysis Exon 18-21 ^Featured

Test CodeP EGFR

AssociationsNSCLC,Non Small-cell Lung Cancer,Response to EGFR tyrosine kinase inhibitors; Gefitinib, Erlotinib, IRESSA, Tarceva Responsiveness in NSCLC

MethodologyReal-time Polymerase chain reaction for exon 18-21. EGFR mutation is a referred test.

Epidermal Growth Factor Receptors (HER1) by IHC

Test CodeI HER1

AssociationsPrognostic marker Overexpressed in breast cancer, lung, brain, bladder, gastric, esophagus, cervix, ovary and endometrium.

MethodologyImmunohistochemistry CONFIRM™ anti-Epidermal Growth Factor Receptor (3C6) Primary Antibody.

Estrogen Progesterone Receptors by IHC

Test CodeI ERPR

AssociationsBreast cancer

MethodologyImmunohistochemistry CONFIRM™ anti-Estrogen Receptor (clone SP1)Primary Antibody CONFIRM anti-Progesterone Receptor (clone 1E2) Primary Antibody