Human papillomavirus genotyping
HPV G
Associations:
HPV Geno
CPT Code:
83891 - Molecular isolation
83892 x4 - Enzymatic digestion
83896 x6 - Each nulcleic acid probe
83903 x2 - Mutation scanning each
88908 x2- Amplfication each sequence
83912 -
Interpretation and report
Turnaround Time:
7-10 days
Methodology:
Third Wave® Technology INVADER®
Specimen Requirements:
2mL liquid cytology media ( ThinPrep PAP solution or TriPath Imaging SurePath™ Test Pack solution)
Causes for Rejection:
Insufficient specimen, low sample cellularity
Specimen Stability:
Stable at 18-25°C for 21 days
Storage and Handling:
Ship at ambient
Reference Range:
HPV HR type 16, 18 or 16/18 Detected/Not Detected
Indication:
Reflex test from an HPV HR + ASC-US result or an HPV HR + primary screening result
References:
- Munoz N et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. NEJM 348:518-527, 2003.
- Khan MJ et al. The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice. JNCI 97:1072-1079, 2005.
Associations:
HPV GenoCPT Code:
83891 - Molecular isolation83892 x4 - Enzymatic digestion
83896 x6 - Each nulcleic acid probe
83903 x2 - Mutation scanning each
88908 x2- Amplfication each sequence
83912 - Interpretation and report
Turnaround Time:
7-10 daysMethodology:
Third Wave® Technology INVADER®Specimen Requirements:
2mL liquid cytology media ( ThinPrep PAP solution or TriPath Imaging SurePath™ Test Pack solution)Causes for Rejection:
Insufficient specimen, low sample cellularitySpecimen Stability:
Stable at 18-25°C for 21 daysStorage and Handling:
Ship at ambientReference Range:
HPV HR type 16, 18 or 16/18 Detected/Not DetectedIndication:
Reflex test from an HPV HR + ASC-US result or an HPV HR + primary screening resultReferences:
- Munoz N et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. NEJM 348:518-527, 2003.
- Khan MJ et al. The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice. JNCI 97:1072-1079, 2005.
