See associations below
|I KAP ISH||Kappa|
|I LAM ISH||Lambda|
|IEBER ISH||Epstein Barr virus|
|* Sent to referral lab|
|HPV P*||HPV DNA In-Situ Hybridization|
Chromogenic in-situ Hybridization (CISH)
Paraffin embedded tissue block
3 slides (3-5 uM) per marker on adhesion glass
Ship ambient. Protect from extreme temperature with an ice pack. Separate ice pack from specimen.
Improper specimen labeling; Inadequate tissue evaluation; Improper sample submission
CISH is an advanced method for detection of gene amplification using a micro-polymer reaction. This technique eliminates the significant background staining associated with non-specific IgG cross reactivity, which can occur with conventional Kappa and Lambda immunohistochemistry (IHC) antibody preparations.
CISH is especially useful for hematologic bone marrow samples and where a plasma cell population is thought to be significant such as in hip fractures.