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Infectious Disease Markers by Immunohistochemistry (IHC)

Test Code

See associations below

Associations
table header column 1 table header column2
I CMV Cytomegalovirus
I HSV Herpes simplex virus type I, II
I HHV8 HHV8 Human Herpesvirus type 8
I PYLORI H.pylori
  Sent to referral lab*
I VZV* Varicella zoster virus

 

Methodology

Immunohistochemistry
Technical component (TC) available for all markers.

Turnaround Time

2 days

Specimen Requirements
  • Formalin fixed tissue
  • Formalin fixed paraffin embedded tissue (preferred)
  • 3 slides (3-5 uM) per marker on adhesion glass
    Specimen Stability
    Indefinitely at room temperature
    Storage & Handling

    Ind

    • Ship ambient. Protect from extreme temperature with an ice pack. Separate ice pack from specimen.
      Causes for Rejection

      Inadequate fixation; Improper labeling

      Reference Range

      Inadequate fixation; Improper labeling

      Description

      Results are reviewed by a board-certified pathologist to determine if tissues are positive or negative for the marker. These results may be used to assist in determining appropriate patient therapy or treatment.
      Immunohistochemistry combines the principles of histochemistry with the high degree of molecular specificity of the antibody-antigen reaction. The use of an enhanced-polymer detection system provides many benefits including increased sensitivity, fewer procedural steps as compared to conventional techniques, and a reduction in non-specific background staining. 


      MPLN offers a range of markers by Immunohistochemistry including hematologic, tissue specific, infectious agents and proliferation antigens.

      References
      1. Press M et al. (2002). Steroids. 67:799-813.
      2. Perttschuk et al. (1996). Cancer. 77:2514-15.
      3. Battifora et al. (1993). Appl Immunohistochem. 1:39-45.