Hematologic Abnormalities and Malignancies
Microscopic evaluation of peripheral blood specimens on smears and from EDTA or NaHep
Ship samples ambient temperature
Improper specimen labeling; Inadequate smear preparations or peripheral blood volume for evaluation; Aged (old) specimens can render material uninterpretable
A board-certified hematopathologist / pathologist evaluates peripheral blood morphology cellular characteristics for abnormality and malignancy, in context with provided clinical information and ancillary clinical findings. Submission of CBC data is required for optimal interpretations. Results of flow cytometric, immunohistochemical, cytogenetic or molecular analyses, when performed, are integrated in the final report.
Clodfelter, R.L., Jr. The peripheral smear. Emerg. Med. Clin. North. Am. 4(1):59-74, 1986