Recurrent genetic abnormalities including BCR-ABL, PML-RARA, AML1-ETO translocations and MLL and CBFB changes are critical to diagnosis, risk stratifications, therapy and disease monitoring of hematologic malignancies. However, low levels of many leukemia-associated genetic changes are incidentally found in normal, healthy individuals. What is the prevalence of such changes in normal individuals?
Reporting in the Journal of Molecular Diagnostics, senior…
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