See associations below
CISH, ISH
| Test Code | Description |
|---|---|
| I KAP ISH | Kappa |
| I LAM ISH | Lambda |
| IEBER ISH | Epstein Barr virus |
| * Sent to referral lab | |
| HPV P* | HPV DNA In-Situ Hybridization |
Chromogenic in-situ Hybridization (CISH)
2 days
Paraffin embedded tissue block
3 slides (3-5 uM) per marker on adhesion glass
Ship ambient. Protect from extreme temperature with an ice pack. Separate ice pack from specimen.
Improper specimen labeling; Inadequate tissue evaluation; Improper sample submission
CISH is an advanced method for detection of gene amplification using a micro-polymer reaction. This technique eliminates the significant background staining associated with non-specific IgG cross reactivity, which can occur with conventional Kappa and Lambda immunohistochemistry (IHC) antibody preparations.
CISH is especially useful for hematologic bone marrow samples and where a plasma cell population is thought to be significant such as in hip fractures.