See associations below
Test Code | Description |
---|---|
I CK5/P63 | Cytokeratin 5/P63, tumor suppressor gene cocktail |
I CK8/18 | Cytokeratin 8/18, adenocarcinoma |
I HMB45 | Melanoma associated marker |
I MC | Melanoma cocktail (HMB-45, MelanA) |
I MELANA | Melanoma associated marker/Mart 1 |
I P16 | p16 tumor suppresor protein |
I P63 | p63 tumor suppressor gene protein nuclear |
I SMM | Smooth muscle myosin |
I S100 | S100 protein |
I TYR | Tyrosinase |
I VIM | Vimentin |
* Performed at affiliate laboratory | |
I CLLG IV* | Collagen IV, basement membrane protein |
Immunohistochemistry
Technical component (TC) available for all markers
2 days
Paraffin embedded tissue block
3 slides (3-5 uM) per marker on adhesion glass
Ship ambient. Protect from extreme temperature with an ice pack. Separate ice pack from specimen.
Inadequate fixation; Improper labeling
Marker and tissue specific
Results are reviewed by a board-certified pathologist to determine if tissues are positive or negative for the marker. These results may be used to assist in determining appropriate patient therapy or treatment.
Immunohistochemistry combines the principles of histochemistry with the high degree of molecular specificity of the antibody-antigen reaction. The use of an enhanced-polymer detection system provides many benefits including increased sensitivity, fewer procedural steps as compared to conventional techniques, and a reduction in non-specific background staining.
MPLN offers a range of markers by Immunohistochemistry including hematologic, tissue specific, infectious agents and proliferation antigens.