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Careers

Careers

Employment Opportunities

MPLN is currently offering a range of career opportunities in diagnostics, including molecular, cytogenetics, flow cytometry, and anatomic pathology. We also have careers for professionals in research and clinical trials, business development, sales, marketing, client services, and operations. 

Our laboratory is located in the foothills of the Great Smoky Mountains, just 20 minutes away from Knoxville, Tennessee. We offer a flexible benefit package that includes a 401k plan, medical, dental, vision, and life insurance, as well as short and long term disability options.

Current Positions

Current Positions

  1. 1
    Genomics and NGS Scientist

    About Us:

    Molecular Pathology Laboratory Network, Inc. (MPLN) and its research division Geneuity Clinical Research Services (MPLN/Geneuity) is a privately held laboratory accredited by the College of American Pathologists (CAP), New York State Department of Health, and ISO15189. We offer molecular pathology diagnostic laboratory and contract clinical research services specializing in oncology, infectious disease, women's health, and clinical trials.

    With over 30 years of experience in the CAP/CLIA diagnostic laboratory and 15 years supporting oncology clinical trials as a contract research organization, our company is positioned for significant, sustained growth.

    Job Overview:

    We seek a highly skilled and motivated Genomics and Next Generation Sequencing Scientist to join our dynamic team. This role focuses on the development, optimization, and implementation of high-throughput genomics workflows, with a strong emphasis on next-generation sequencing (NGS) and automation technologies. The ideal candidate will bring experience in clinical research environments and possess a deep understanding of genomic data generation, interpretation, and the potential clinical applications of NGS.

    Key Responsibilities:

    • Guide decisions on suitable test development using Next Generation Sequencing and other advanced molecular technologies
    • Design, validate, and implement automated NGS workflows for clinical applications, which include DNA/RNA extraction, library preparation, sequencing, and data analysis
    • Develop and maintain documentation, including SOPs, validation reports, and technical protocols
    • Provide technical expertise and training to laboratory and research staff
    • Collaborate among departments to support integrated clinical testing workflows
    • Ensure compliance with CLIA, CAP, and other regulatory guidelines for clinical genomics operations
    • Conduct quality control and troubleshoot genomic assays and automation platforms
    • Analyze and interpret complex genomic data to support diagnostic and translational research initiatives

    Qualifications:

    • Ph.D. in Genetics, Molecular Biology, Genomics, Bioinformatics, or a related field
    • More than 3 years of experience in a clinical genomics setting, with hands-on expertise in NGS technologies and automation systems
    • A strong knowledge of automation or bioinformatics tools and pipelines for NGS data analysis is an advantage
    • Familiarity with regulatory requirements in clinical genomics, such as CLIA, CAP, and HIPAA
    • Excellent problem-solving skills and attention to detail
    • Strong communication and collaboration skills in interdisciplinary team settings

    Preferred Experience:

    Experience with Illumina or other major NGS platforms

    Experience in automation programming and scripting

    Candidates must pass a pre-employment drug screen and background check.

    MPLN is an equal opportunity employer.

Submit Your Résumé

To apply, submit your résumé to hr@mplnet.com, or submit the form below using the HR/Careers option.

    Project Management

    Our project managers have strong scientific backgrounds and extensive experience in complex research-based clinical trials. They collaborate with our scientific operations, client services, and commercial operations teams to deliver high-quality, regulatory-compliant testing results on time at every project step.

    Key Features

    • Each study is assigned a dedicated and experienced project manager
    • Studies are typically set up within 6 to 8 weeks of contract signature
    • Project management software tools ensure timely deliveries
    • Onsite customer service teams efficiently resolve queries and deliver reports

    Benefits

    • Accelerated study setup time
    • Responsive communication with the scientific and operational team
    • Testing completed on time and within budget
    • Prompt reporting of critical study data

    Data Management

    The key to a successful clinical trial is accurate, clean, quality data. Our team of data managers provides you with data in customized formats exported to your data management teams from our in-house laboratory information system (LIS).

    Key Features

    • Access to dedicated and experienced data specialists upon contract award
    • Customized reports are agreed upon in study-specific data transfer agreement
    • In-house software development team for custom data solutions
    • Flexible data exports and data transfers

    Benefits

    • Real-time reports for your data and project teams to aid in patient management
    • Guaranteed data integrity and quality
    • Improved decision-making and enhanced patient safety
    • Timely access to accurate, clean data for intermediate or final database lock
    Genomic Solutions

    Genomic Solutions

    Genomic medicine, a vital tool in oncology and drug development by providing deeper, more personalized insights into each patient.

    Beyond informing drug target discovery, validation, and clinical development, it uncovers critical genetic markers that drive disease progression and influence individual treatment responses. This empowers healthcare professionals to create more precise, tailored treatment plans, optimizing medical management based on each patient’s genetic profile.

    DNA Solutions – WGS*, WGMS*, WES*, TSO-500 Comp, Pillar OncoReveal
    RNA Solutions – Total RNA-Seq*, RNA exome*, mRNA*
    Liquid Biopsy Solutions – TSO-500 ctDNA, PGDx elio™ plasma complete*

    Key Features

    • Targeted NGS panels, including FDA-approved assays with companion diagnostic designations
    • Customized bioinformatics and reporting solutions 
    • Robust assay designs to accommodate low-yielding biopsy material
    • Streamlined wet lab processes to meet screening window timelines

    Benefits

    • Identify variants along with key biomarker signatures
    • Save time and money by assessing multiple biomarkers in a single test
    • Enable targeted therapies with actionable, easy-to-interpret results
    • Assists in targeted patient stratification and recruitment
    • Accelerates the development of personalized medicine

    *Offered through fully accredited partner laboratories.

    Digital Pathology

    Digital Pathology

    Digital pathology revolutionizes clinical trials by enhancing accessibility, cost-efficiency, compliance, and data management. MPLN’s comprehensive digital pathology services streamline clinical research, allowing for improved patient outcomes and operational efficiency.

    Key Features

    • Seamless access to digital slides and slide retrieval enables instant access to digital slides.
    • Cost-effective digital slide management streamlines logistics by reducing the need for physical slide storage and transportation.
    • Digital storage ensures slides remain in perfect condition over time.

    Benefits

    • Allows key opinion leaders (KOL) and remote client pathologists to be utilized
    • Digital slides can be easily shared, allowing for faster, more collaborative decisions, including obtaining second opinions.
    • Reduces the costs associated with physical storage and transport of slides, improving trial efficiency.
    • Simplifies regulatory processes, ensuring quicker and more accurate FDA submissions and audit readiness.
    • Prevents slide degradation or breakage, maintaining the quality of research data for the long term.
    • Enables broader patient recruitment by facilitating decentralized clinical trials for wider geographic participation, increasing patient recruitment and diversity.
    Global Logistics

    Global Logistics

    Effective global logistics are the cornerstone of effective specialty laboratory testing supporting global clinical trials. With precious patient samples such as biopsy and bone marrow aspirates, ensuring samples reach the lab on time and within stability is paramount.

    Key Features

    • Partnerships with global specialist couriers and large integrators to support global studies and specialty shipping requirements
    • Ambient, refrigerated, frozen, and liquid nitrogen storage and shipment services available
    • Real-time or batched shipments based on your clinical trial’s individual needs
    • Secure, high-volume, redundant data storage solutions for digital pathology images
    • Expert advice for effective sample collection, handling, and transport
    • Accurate tracking and inventory for all clinical trial specimens

    Benefits

    • Safe and effective transport of specimens worldwide
    • Standardized procedures to reduce pre-analytical variability and ensure valid results
    • Centralized and harmonized specialty pathology testing supported
    • Reduced costs and maximized budgets with fully managed logistics from one trusted source
    • Readily available inventories, manifests, and shipments for timely study closeouts
    Multiplex IHC clinical trial services

    IHC & Multiplex IHC

    Our advanced technology enables simultaneous visualization of single or multiple biomarkers within the same tissue section, delivering comprehensive insights and precise diagnostics. With unmatched expertise and cutting-edge technology, our team supports you in understanding complex tissue microenvironments, aiding patient stratification and treatment response prediction.

    Key Features

    • Simultaneously visualize multiple biomarkers within the same tissue section for deeper insights.
    • Advanced analysis of tissue microenvironments to assist in patient stratification and treatment response prediction.
    • Custom assay design and flexible testing to meet your unique research or clinical trial needs.
    • Our expert team provides detailed data analysis and interpretation to ensure accurate results.

    Benefits

    • Allows enhanced information from small biopsy samples. (I.e. NSCLC)
    • Gain comprehensive insights that lead to more precise diagnostics and better patient outcomes.
    • Enhanced ability to identify patient subgroups and better predict treatment responses more accurately.
    • Whether in biomarker discovery or clinical trials, our advanced technology supports a range of applications, helping you unlock the full potential of your tissue samples.
    Cytogenetics FISH - clinical trial services

    Cytogenetics & FISH

    We offer a comprehensive range of chromosome analysis and fluorescent in situ hybridization (FISH) testing with industry-leading turnaround times and global coverage. Our board-certified lab directors and experienced cytogenetic technologists ensure accurate, efficient, and competitively priced testing with the highest quality of service.

    Key Features

    • Extensive FISH menu of over 40 loci and disease-specific panels detecting gene amplifications, deletions, translocations, and inversions.
    • Testing is available on bone marrow, blood, and FFPE tissue samples.
    • Specialized Offerings:
      • Plasma cell enrichment for plasma disorders
      • Stat turnaround for PML::RARA and acute myeloid leukemia
      • Bladder cancer urine analysis
      • Custom FISH assay development
    • Comprehensive chromosome analysis testing for oncology, infertility, recurrent pregnancy loss, and congenital disorders.
    • Global coverage of equivocal CAP/CLIA services supporting clinical trials

    Benefits

    • Rapid, precise results critical for diagnosis and treatment.
    • Expert-driven testing with Board-certified experts ensures the highest accuracy.
    • Tailored assays and solutions to meet unique clinical needs.
    • Faster diagnostics support timely treatment decisions.