Cellular Immunology

Molecular Pathology Laboratory Network, Inc. (MPLN) has been a leader in laboratory medicine since its establishment. Our Flow Cytometry technologists, utilizing state-of-the-art instrumentation, specialize in cellular immunology. They offer a comprehensive range of services to diagnose and monitor hematologic disorders and therapeutic immune responses.

Clinical Utility

Immunophenotypic analysis by multiparameter flow cytometry is a powerful tool in the evaluation of hematolymphoid neoplasia. At MPLN, interdisciplinary testing on a single sample is reviewed closely to enhance the flow cytometry data; this includes clinical, morphologic, molecular, and genetic findings.

By analyzing the expression of cell surface and cytoplasmic markers, abnormal cells can be identified, enumerated, and characterized with respect to cell lineage and maturation. The sensitivity of the technology and the ability to process and analyze large amounts of data quickly allows flow cytometry to be used to:

Characterize/classify
- Hematolymphoid neoplasia
- Myelodysplastic/myeloproliferative processes
- Acute leukemias
- B-cell neoplasms
- Plasma cell disorders
- T-cell/NK cell neoplasms
- Rare/unusual processes (mast cell disorders, etc.)
Determine proliferative rates of lymphomas
Determine treatment efficacy/monitor for
residual disease

Multiparameter Immunophenotyping by Flow Cytometry

Flow cytometry is one of the principal tools used for immunophenotyping, receptor occupancy testing, and MRD detection, all of which are critical for patient management and late-stage research investigations. Our flow cytometry services include:

Comprehensive lymphoma and/or leukemia immunophenotyping
Lymphocyte screening (B, T, NK cells)
Monoclonal gammopathy (B-cell, plasma cell)
Residual disease (specified)
PNH
Customized receptor occupancy assays
Other special markers
Peripheral blood mononuclear cell (PBMC) isolation

Innovative. Comprehensive. Consultative.

Designed to provide accurate, reliable, and clinically relevant data in a timely fashion.

Streamlined ordering/reporting to simplify reflex testing
One source for ancillary testing
Rapid turnaround time
Post analytic review for quality assurance
Individual case management solving clinical problems

Coordinating laboratory tests and results within one facility, MPLN provides a single source for flow cytometry, anatomic pathology, genetics, cytogenetics, and molecular testing. Using one source for your laboratory testing provides simpler logistics for ordering, molecular reflex testing, reporting, billing, and patient management.

Our cellular immunology consultancy undertakes rigorous research to decipher the workings of your immune system. We stay up-to-date with the latest breakthroughs in analysis and diagnosis of diverse immune system-related conditions. Our proficient team of experts utilize advanced technology to provide personalized solutions to your distinctive immune profile. Our laboratory boasts state-of-the-art equipment providing precision, accuracy, and sensitivity, which enable us to diagnose an array of ailments including immunodeficiency, autoimmune diseases, allergies, among others. We prioritize the patient’s well-being and our goal is to administer the most efficient, secure, and economical treatments. Our competence helps you realize the latent potential of your immune system and to assume control of your health. Kindly contact us to learn more about the cutting-edge cellular immunology services we offer.

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