M CF 39
Cystic fibrosis carrier and diagnostic
Polymerase chain reaction (PCR) / Allele Specific Primer Extension (ASPE)
5.0 mL (min. 3.0 mL) whole blood EDTA preferred, ACD accepted
Ship blood specimen at ambient temperature.
If shipment is delayed, store blood at 2–8°C and ship with a cool/refrigerated pack.(Do not allow the sample to be in direct contact with the cool pack.)
Insufficient DNA material; Frozen; Clotted; Severely hemolyzed whole blood specimen; frozen sample
The Luminex xTAG® Cystic Fibrosis (CFTR) 39 kit v2 (IVD) allows for the detection and simultaneous identification of a panel of 39 mutations and 4 variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The panel includes mutations and variants currently recommended by the American College of Medical Genetics and American College of Obstetricians and Gynecologists (ACMG/ACOG), as well as additional mutations found to be prevalent in more ethnically diverse North American populations.
Population-based CF carrier screening is recommended for:
Individuals with a family history of CF
Reproductive partners of individuals with CF
Couples who are planning a pregnancy or seeking prenatal care
xTAG is a trademark of Luminex