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GIST Panel - KIT, PDGFRA, BRAF by Next Generation Sequencing

Test Code

M GIST MUT

Test Synonyms

KIT−exons 9, 11, 13, and 17
PDGFRA−exons 12 and 18
BRAF

Associations

GIST

Methodology

Next Generation Sequencing Targeted HotSpots
QIAGEN® Human Tumor Actionable Mutations Panel (GeneRead™ DNAseq Targeted Panels V2) for targeted enrichment

Turnaround Time

7-10 days

Specimen Requirements

Formalin Fixed Paraffin Embedded tissue block or slides (3-5 slides at 5 micron minimum) NOTE: Include a surgical pathology report with the sample

Specimen Stability
Indefinite at ambient temperature (18-25°C)
Storage & Handling

Ship at ambient temperature, cool in summer. (Do not allow cool/refrigerated pack to directly contact sample)

Causes for Rejection

Improper specimen labeling; Insufficient sample volume

Description

Detects activating mutations in BRAF, KIT and PDGFRA. Predicts response to tyrosine kinase inhibitor (TKI) therapy.

Trademarks

Qiagen and GeneRead are trademarks of Qiagen