See associations below
Sarcoma, Vascular, Neural, Fibrohistiocytic, Muscle, GIST, Stromal Markers
|I ALK||Anaplastic lymphoma kinase - 1|
|I CD10||Common ALL antigen|
|I CD31||CD31 endothelial cells|
|I CD34||CD34 endothelial, stem cells, stromal cells|
|I CD56||NK cell|
|I CD99||Ewings sarcoma, PNET|
|I CD117||CD117 C-kit, myeloid and mast cell|
|I D2 40||D2-40, Podoplanin|
|I DESMIN||Desmin filament protein|
|I DOG1||DOG1, derived from GIST 1|
|I EMA||Epithelial membrane antigen|
|I FXIIIA||Factor XIIIa fibrohistiocytic, dendritic cells|
|I MSA||Muscle Specific Actin|
|I MYOGEN||Myogenin muscle marker|
|I MYOGLB||Myoglobin cardiac, skeletal|
|I PDGFR||Platelet derived growth factor receptor alpha|
|I S100||S100 protein|
|I SMA||Smooth muscle actin|
|I SMM||Smooth muscle myosin|
|I WT1||Wilms tumor|
Technical component (TC) available for all markers.
Formalin fixed tissue
Formalin fixed paraffin embedded tissue (preferred)
In extreme hot weather ship with a cool pack.
Inadequate fixation; Improper labeling
Marker and tissue specific
Results are reviewed by a board-certified pathologist to determine if tissues are positive or negative for the marker. These results may be used to assist in determining appropriate patient therapy or treatment.
Immunohistochemistry combines the principles of histochemistry with the high degree of molecular specificity of the antibody-antigen reaction. The use of an enhanced-polymer detection system provides many benefits including increased sensitivity, fewer procedural steps as compared to conventional techniques, and a reduction in non-specific background staining.
MPLN offers a range of markers by Immunohistochemistry including hematologic, tissue specific, infectious agents and proliferation antigens