All posts by: Paul Travis

by in Flow Cytometry

Case Study – Flow Cytometry

Case Study Unusual Acute Promyelocytic Leukemia, reflexed for FISH analysis; t(15;17) positive. Histogram 1: Promyelocytes isolated by SSC v CD45 Histogram 2: CD34 negative/CD117 positive promyelocytes (expected) Histogram 3: CD11b negative (expected), HLA DR positive (unusual). The specimen was reflexed for PML/RARA fusion by fluorescence in situ hybridization and was positive. Comprehensive PanelsSamples are received […]

by in Biopharma, Multiplex Immunohistochemistry

Myelodysplastic Syndromes Global Support

For myelodysplastic syndromes, current therapy is selected based on risk, transfusion needs, percent of bone marrow blasts, cytogenetic and mutational profiles, comorbidities, potential for allogeneic stem cell transplantation (alloSCT), and prior exposure to hypomethylating agents (HMA). Better diagnosis and prognostic stratification may allow a more precise and personalized treatment of MDS with novel agent combinations, […]